post-transcriptional regulation

Upregulation of 5′-terminal oligopyrimidine mRNA translation upon loss of the ARF tumor suppressor
Loss of the tumors supressor ARF causes increased translation of 5’-TOP mRNAs.
Kyle A. Cottrell, Ryan C. Chiou, Jason D. Weber
PDF DOI
Upregulation of 5′-terminal oligopyrimidine mRNA translation upon loss of the ARF tumor suppressor
A short translational ramp determines the efficiency of protein synthesis
5’ codons influence the efficiency of protein synthesis.
Manasvi Verma, Junhong Choi, Kyle A. Cottrell, Zeno Lavagnino, Erica N. Thomas, Slavica Pavlovic-Djuranovic, Pawel Szczesny, David W. Piston, Joseph D. Puglisi, Sergej Djuranovic
PDF DOI
A short translational ramp determines the efficiency of protein synthesis
PTRE-seq reveals mechanism and interactions of RNA binding proteins and miRNAs
PTRE-seq is system for massively parallel functional analysis of 3’UTR elements.
Kyle A. Cottrell, Hemangi G. Chaudhari, Barak A. Cohen, Sergej Djuranovic
PDF DOI
PTRE-seq reveals mechanism and interactions of RNA binding proteins and miRNAs
Translation efficiency is a determinant of the magnitude of miRNA-mediated repression
miRNA-mediated repression is influenced my multiple cis elements and translation efficiency.
Kyle A. Cottrell, Pawel Szczesny, Sergej Djuranovic
PDF DOI
Translation efficiency is a determinant of the magnitude of miRNA-mediated repression
Urb-RIP – An Adaptable and Efficient Approach for Immunoprecipitation of RNAs and Associated RNAs/Proteins
Urb-RIP is a method for immunoprecipitation of RNPs.
Kyle A. Cottrell, Sergej Djuranovic
PDF DOI
Urb-RIP – An Adaptable and Efficient Approach for Immunoprecipitation of RNAs and Associated RNAs/Proteins